Highly enantioselective synthesis of syn-aldols of cyclohexanones via chiral primary amine catalyzed asymmetric transfer aldol reactions in ionic liquid.
نویسندگان
چکیده
Chiral primary-tertiary diamine/TfOH was found to catalyze kinetic resolution of racemic syn-aldols of cyclohexanones in ionic liquid effectively, affording the chiral syn-aldols with up to 99:1 syn/anti and 99% ee.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 6 شماره
صفحات -
تاریخ انتشار 2011